Multi-Column Continuous Chromatography System and Automated Viral Inactivation System

Organisation

Cell & Gene Therapy Catapult

12th Floor Guys Hospital, London, SE1 9RT

Lot 1 - Multi-column Continuous Chromatography System CGTC are looking for the purchase and installation of a multi-column chromatography system (MCCS) and related services e.g service, repair and maintenance contract, training and consumables for our Braintree Essex site. The instrument will be a fully automated chromatography system applicable for biopharmaceutical production. The main key feature of the multi-column chromatography technology is the use of a series of interconnected columns allowing the first column to reach breakthrough during loading which significantly improves the utilisation of the chromatographic resin or membrane. A typical application of the technology is for capture chromatography however it is not limited to it.

Viral Inactivation Hardware System he system must provide automated viral inactivation processing including the following steps: a) controlled mixing b) pH measurement e.g. via probe or single-use sensor integrated into single-use bioprocessing vessel and/or tubing set c) automated pH adjustment e.g via dosing pumps d) batch execution control e.g. via programmable software or HMI screen e) GMP batch data capture f) product vessel volume/mass monitoring e.g. via load cells g) temperature control of liquid product contained in single-use bioprocessing vessel and/or tubing set h) temperature monitoring of liquid product contained in single-use bioprocessing vessel and/or tubing set

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Application Deadline

17 November 2026

26 days left

Estimated Value

£1,600,000

WAC Reference

WAC-676217

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