Establishment of a Termed agreement for the supply of Centrifugal evaporators and HCI-resistant centrifugal evaporators for high-throughput of solvents after purification of small-molecule and peptide samples by preparative HPLC or reverse phase column chromatography, and to lyophilize final compounds.
Establishment of a Termed Supply & Service Agreement for Vacuum Pump Systems. Immediate requirement covering three (3) - five (5) years in the first instance. With scope to extend by an additional five (5) x 12 months subject to need and satisfactory performance.
Provision of Service, Maintenance, Repair, Calibration, Insurance Inspections of BMM Weston Autoclaves installed within the Life Science. 5 x 12 month agreement - Total Value of expenditure over the 4 years is estimated as 100000.00 GBP
Provision of Service & Maintenance of Autoclaves installed within the University of Dundee - estimated value applies to cumulative total spend value for the term, the University is not bound to spend this value and has been advised as information only. Initial requirement is for the service & maintenance of Autoclaves installed within the School of Life Science, managed by Central Technical Services.(5 x 12 months)
Establishment of a Termed agreement for the supply of Centrifugal evaporators and HCI-resistant centrifugal evaporators for high-throughput of solvents after purification of small-molecule and peptide samples by preparative HPLC or reverse phase column chromatography, and to lyophilize final compounds.
The University of Dundee wishes to enter into a Framework Agreement with one contractor for the
design, upgrading and replacement of mechanical and electrical installations within various properties owned, occupied or otherwise used by University of Dundee.
This contract involves the statutory programmed servicing, performing repairs and LEV call outs across the University campus. The Supplier will appoint a, ’Residential Engineer,’ who will exclusively carry out works only for the University of Dundee and will not carry out works on any sites out with the bounds of this contract. The Residential Engineer will be exclusively at the disposal of the University for additional items such as user training and overseeing commissioning works. However, sufficient time allocation must be allowed for the statutory annual servicing/validation programme to be satisfied.
Second-Generation Framework for the provision of Chemistry Synthesis and other Chemistry Services Outsourcing with initial term of two (2) years with the option to extend for up to 2 x 12 months, if required, at the sole discretion of the University and subject to ongoing satisfactory performance by the appointed Service Providers.
The Services will include:
1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;
2.Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;
3. Scale up of chemistry, up to 200g;
4.Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.
5.Synthesis of intermediates at 5-100g;
For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;
6. Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.