The Genomics Core Facility (GCF), within Newcastle University, is a state-of-the-art Next-Generation Sequencing laboratory that specialises in single-cell and spatial transcriptomics applications and supports a wide range of sequencing-based research within the Faculty of Medical Sciences (FMS) and beyond. The sequencing technology currently available within the facility is based on a clonally amplified short-read approach. As part of an MRC equipment award the University are seeking to purchase a high-throughput, scalable, long-read single-molecule sequencer. The scope of the contract is for the supply of the equipment and proprietary consumables, delivery, installation, training, 4 years of maintenance and servicing cover to begin once the 12-month warranty period has expired and proprietary consumables for 5 years post installation (to be purchased as and when required). The sequencer will be operated by dedicated and experienced NGS staff and will play a central role in large-scale discovery and translational research programmes involving genomic, transcriptomic, epigenomic and single cell analysis.
Newcastle University's Genomics Core Facility (GCF) is a state-of-the-art Next-Generation Sequencing laboratory that specialises in single-cell and spatial transcriptomics applications and supports a wide range of sequencing-based research within the Faculty of Medical Sciences (FMS) and beyond. The sequencing technology currently available within the facility is based on a clonally amplified short-read approach. As part of an MRC equipment award the University are seeking to purchase a high-throughput, scalable, long-read single-molecule sequencer. The scope of the contract is for the supply of the equipment and proprietary consumables, delivery, installation, training, 4 years of maintenance and servicing cover to begin once the 12-month warranty period has expired and proprietary consumables for 5 years post installation (to be purchased as and when required). The sequencer will be operated by dedicated and experienced NGS staff and will play a central role in large-scale discovery and translational research programmes involving genomic, transcriptomic, epigenomic and single cell analysis.
The Newcastle University Translational and Clinical Research Institute is one of three research institutes established in 2019 following a restructure within the Faculty of Medical Sciences. Its members map across the biomedical research landscape. A number of major research projects are led from within the Institute including the "NASH Disease Translational Accelerator" (NASH-DTA) project. This project funded brings together clinicians and scientists from prominent academic centres across Europe and industrial partners to conduct research into advanced liver disease/cirrhosis caused by non-alcoholic fatty liver disease (NAFLD). Their common goals are developing, validating and qualifying better biomarkers for NAFLD. Strongly associated with the epidemics of obesity and type 2 diabetes that are testing healthcare systems worldwide, NAFLD is an increasingly common cause of advanced liver disease that is characterized by substantial inter-patient variability in severity and rate of progression. Biomarkers under investigation in the project include genes that contribute to NAFLD progression.
The purpose of this tender process is to engage a supplier to provide clinical research support, central laboratory services and to oversee biological sample transfers and provide centralised laboratory processing of biological samples collected during the course of the study.
The Newcastle University Translational and Clinical Research Institute is one of three research institutes established in 2019 following a restructure within the Faculty of Medical Sciences. Its members map across the biomedical research landscape. A number of major research projects are led from within the Institute including the “NASH Disease Translational Accelerator” (NASH-DTA) project. This project funded brings together clinicians and scientists from prominent academic centres across Europe and industrial partners to conduct research into advanced liver disease/cirrhosis caused by non-alcoholic fatty liver disease (NAFLD). Their common goals are developing, validating and qualifying better biomarkers for NAFLD. Strongly associated with the epidemics of obesity and type 2 diabetes that are testing healthcare systems worldwide, NAFLD is an increasingly common cause of advanced liver disease that is characterized by substantial inter-patient variability in severity and rate of progression. Biomarkers under investigation in the project include genes that contribute to NAFLD progression.
The purpose of this tender process is to engage a supplier to provide clinical research support, central laboratory services and to oversee biological sample transfers and provide centralised laboratory processing of biological samples collected during the course of the study.
This tender is to establish a Contract for services to collect, transport and dispose of wastes from human and/or animal healthcare and/or related research.
The objectives of the Contract are to:
• Provide a compliant, resilient, efficient, and cost-effective service , undertaking, and managing the safe collection, handling, transport, and disposal of segregated wastes from University sites to the point of final disposal.
• Achieve zero to landfill on all waste streams, including treated and non-hazardous waste.
• Reduce the carbon footprint of the University’s waste activities by moving waste up the Waste Hierarchy.
• Provide monthly accurate University specific data on waste weights, uplifts, categories, transport miles, treatment type and associated CO2 equivalent emissions.
• Support the University to train staff in ‘best practice’ waste management principles, to reduce waste and improve segregation.
• Seek to continually improve the service delivered and develop sustainable waste minimisation, reuse, and recycling opportunities wherever possible.
• Maintain and continually demonstrate full compliance with all regulatory requirements and applicable codes of practice.
The awarded contract will focus on logistical and service improvements, minimisation in environmental impact and movement up the Waste Hierarchy as well as cost efficiency.
The desired services are presented and will be awarded according to Lots. Each Lot is based around the characteristics, collection requirements or potential outcomes of the waste streams in question.
Lots will be awarded exclusively to the successful Provider; however, it is not possible or desirable to guarantee tonnages within each Lot.
Providers may tender for more than one Lot:
• Lot 1 - Hazardous healthcare and related research wastes requiring treatment prior to disposal (AT) or High Temperature Incineration (HTI)
• Lot 2 - Non-Hazardous Healthcare and Related Research Wastes (appropriate for e.g., municipal waste to energy disposal
• Lot 3 – Chemically Contaminated Laboratory Waste from Research and Teaching
Contracts will be awarded for a period of 3 years (36 months) with an option for a further two, one-year (12 month) extensions at the agreement of both parties.
University of Newcastle upon Tyne t/a Newcastle UniversityNorth EastWAC-273759
This tender is to establish a Contract for services to collect, transport and dispose of wastes from human and/or animal healthcare and/or related research.
The objectives of the Contract are to:
• Provide a compliant, resilient, efficient, and cost-effective service, undertaking, and managing the safe collection, handling, transport, and disposal of segregated wastes from University sites to the point of final disposal.
• Achieve zero to landfill on all waste streams, including treated and non-hazardous waste.
• Reduce the carbon footprint of the University's waste activities by moving waste up the Waste Hierarchy.
• Provide monthly accurate University specific data on waste weights, uplifts, categories, transport miles, treatment type and associated CO2 equivalent emissions.
• Support the University to train staff in 'best practice' waste management principles, to reduce waste and improve segregation.
• Seek to continually improve the service delivered and develop sustainable waste minimisation, reuse, and recycling opportunities wherever possible.
• Maintain and continually demonstrate full compliance with all regulatory requirements and applicable codes of practice.
The awarded contract will focus on logistical and service improvements, minimisation in environmental impact and movement up the Waste Hierarchy as well as cost efficiency.
The desired services are presented and will be awarded according to Lots. Each Lot is based around the characteristics, collection requirements or potential outcomes of the waste streams in question.
Lots will be awarded exclusively to the successful Provider; however, it is not possible or desirable to guarantee tonnages within each Lot.
Providers may tender for more than one Lot:
• Lot 1 - Hazardous healthcare and related research wastes requiring treatment prior to disposal (AT) or High Temperature Incineration (HTI)
• Lot 2 - Non-Hazardous Healthcare and Related Research Wastes (appropriate for e.g., municipal waste to energy disposal
• Lot 3 - Chemically Contaminated Laboratory Waste from Research and Teaching
Contracts will be awarded for a period of 3 years (36 months) with an option for a further two, one-year (12 month) extensions at the agreement of both parties.
Documents are available free of charge from the e-tender system, ProContract:
https://procontract.due-north.com/Login
All enquiries and questions regarding this tender should be submitted through the e-tender system, ProContract.
University of Newcastle upon Tyne t/a Newcastle UniversityNorth EastWAC-270147
The Biomedical Engineering research hub in the School of Engineering, as well as other research groups in the Faculty of Science, Agriculture and Engineering and Faculty of Medical Sciences at Newcastle University, require a new laser micromachining capability to develop the next generation of biomedical devices – including implantable, diagnostic tools, and advanced therapeutic delivery systems. This purchase is being funded by the Wolfson Foundation.
The scope of this contract is for the supply, delivery and installation of the equipment detailed in the Invitation to Tender documents to the University, with after-sales support and 12 months warranty and maintenance.
Expressions of interest in this project can be made by registering via the University's
etendering portal at: https://procontract.due-north.com/Advert/Index?advertId=ce3b15f4-447d-ed11-811c-005056b64545
The contract reference is NU/1830.
The deadline for expressing an interest in this tender is Tuesday 17th January 2023 at
16:00 hours GMT
The Biomedical Engineering research hub in the School of Engineering, as well as other research groups in the Faculty of Science, Agriculture and Engineering and Faculty of Medical Sciences at Newcastle University, require a new laser micromachining capability to develop the next generation of biomedical devices - including implantable, diagnostic tools, and advanced therapeutic delivery systems. This purchase is being funded by the Wolfson Foundation.
The scope of this contract is for the supply, delivery and installation of the equipment detailed in the Invitation to Tender documents to the University, with after-sales support and 12 months warranty and maintenance.
Expressions of interest in this project can be made by registering via the University's
etendering portal at: https://procontract.due-north.com/Advert/Index?advertId=ce3b15f4-447d-ed11-811c-005056b64545
The contract reference is NU/1830.
The deadline for expressing an interest in this tender is Tuesday 17th January 2023 at
16:00 hours GMT
This tender is to establish a Contract for services to collect, transport and dispose of wastes from human and/or animal healthcare and/or related research.
The objectives of the Contract are to:
• Provide a compliant, resilient, efficient, and cost-effective service, undertaking, and managing the safe collection, handling, transport, and disposal of segregated wastes from University sites to the point of final disposal.
• Achieve zero to landfill on all waste streams, including treated and non-hazardous waste.
• Reduce the carbon footprint of the University's waste activities by moving waste up the Waste Hierarchy.
• Provide monthly accurate University specific data on waste weights, uplifts, categories, transport miles, treatment type and associated CO2 equivalent emissions.
• Support the University to train staff in 'best practice' waste management principles, to reduce waste and improve segregation.
• Seek to continually improve the service delivered and develop sustainable waste minimisation, reuse, and recycling opportunities wherever possible.
• Maintain and continually demonstrate full compliance with all regulatory requirements and applicable codes of practice.
The awarded contract will focus on logistical and service improvements, minimisation in environmental impact and movement up the Waste Hierarchy as well as cost efficiency.
The desired services are presented and will be awarded according to Lots. Each Lot is based around the characteristics, collection requirements or potential outcomes of the waste streams in question.
Lots will be awarded exclusively to the successful Provider; however, it is not possible or desirable to guarantee tonnages within each Lot.
Providers may tender for more than one Lot:
• Lot 1 - Hazardous healthcare and related research wastes requiring treatment prior to disposal (AT) or High Temperature Incineration (HTI)
• Lot 2 - Non-Hazardous Healthcare and Related Research Wastes (appropriate for e.g., municipal waste to energy disposal
• Lot 3 - Chemically Contaminated Laboratory Waste from Research and Teaching
Contracts will be awarded for a period of 3 years (36 months) with an option for a further two, one-year (12 month) extensions at the agreement of both parties.
Documents are available free of charge from the e-tender system, ProContract:
https://procontract.due-north.com/Login
All enquiries and questions regarding this tender should be submitted through the e-tender system, ProContract.
University of Newcastle upon Tyne t/a Newcastle UniversityNorth EastWAC-257618
A Stylus Profiler is required to be used as an integrated part of semiconductor device fabrication facility housed in the class 100/1000 cleanroom at the School of Engineering (SoE) at Newcastle University (NU). This fabrication facility includes 25 workstations covering all technological steps from growth and deposition of thin films to chips packaging and testing. Control of surface topography is critically important in all steps of device microfabrication ensuring optimised processing and reproducibility of results.
This purchase is being funded by the Engineering and Physical Sciences Research Council (EPSRC)
Please review the available documentation via the link on the University e-tender portal, and provide a fully detailed response to our requirements.
The Biomedical Engineering research hub in the School of Engineering, as well as other research groups in the Faculty of Science, Agriculture and Engineering and Faculty of Medical Sciences at Newcastle University, require a new laser micromachining capability to develop the next generation of biomedical devices - including implantable, diagnostic tools, and advanced therapeutic delivery systems. This purchase is being funded by the Wolfson Foundation.
The scope of this contract is for the supply, delivery and installation of the equipment detailed in the Invitation to Tender documents to the University, with after-sales support and 12 months warranty and maintenance.
Expressions of interest in this project can be made by registering via the University's etendering portal at: https://procontract.due-north.com/Advert/Index?advertId=ce3b15f4-447d-ed11-811c-005056b64545
The contract reference is NU/1830.
The deadline for expressing an interest in this tender is Friday 27th January 2023 at 16:00 hours GMT
The Biomedical Engineering research hub in the School of Engineering, as well as other research groups in the Faculty of Science, Agriculture and Engineering and Faculty of Medical Sciences at Newcastle University, require a new laser micromachining capability to develop the next generation of biomedical devices - including implantable, diagnostic tools, and advanced therapeutic delivery systems. This purchase is being funded by the Wolfson Foundation.
The scope of this contract is for the supply, delivery and installation of the equipment detailed in the Invitation to Tender documents to the University, with after-sales support and 12 months warranty and maintenance.
Expressions of interest in this project can be made by registering via the University's etendering portal at: https://procontract.due-north.com/Advert/Index?advertId=ce3b15f4-447d-ed11-811c-005056b64545
The contract reference is NU/1830.
The deadline for expressing an interest in this tender is Friday 27th January 2023 at 16:00 hours GMT
The scope of this contract is for the supply and installation of fluorescence and phosphor imaging system. The offer must include training, for at least 2 personnel, for the safe operation of the equipment and 12 months warranty.
The Newcastle University Translational and Clinical Research Institute is one of three research institutes established in 2019 following a restructure within the Faculty of Medical Sciences. Its members map across the biomedical research landscape. A number of major research projects are led from within the Institute including the "NASH Disease Translational Accelerator" (NASH-DTA) project. This project funded brings together clinicians and scientists from prominent academic centres across Europe and industrial partners to conduct research into advanced liver disease/cirrhosis caused by non-alcoholic fatty liver disease (NAFLD). Their common goals are developing, validating and qualifying better biomarkers for NAFLD. Strongly associated with the epidemics of obesity and type 2 diabetes that are testing healthcare systems worldwide, NAFLD is an increasingly common cause of advanced liver disease that is characterized by substantial inter-patient variability in severity and rate of progression. Biomarkers under investigation in the project include genes that contribute to NAFLD progression. The NASH-DTA project has two parts: retrospective and prospective study. Retrospective study is based on analysing existing samples, prospective study will recruit 200 patients and collect new samples over 5 years.
The purpose of this tender process is to engage a supplier to provide metabolomic analysis on plasma samples from both a retrospective and prospective study using AbsolutelDQ Bile Acids kit and MxP Quant 500 Kit.
The Newcastle University Translational and Clinical Research Institute is one of three research institutes established in 2019 following a restructure within the Faculty of Medical Sciences. Its members map across the biomedical research landscape. A number of major research projects are led from within the Institute including the “NASH Disease Translational Accelerator” (NASH-DTA) project. This project funded brings together clinicians and scientists from prominent academic centres across Europe and industrial partners to conduct research into advanced liver disease/cirrhosis caused by non-alcoholic fatty liver disease (NAFLD). Their common goals are developing, validating and qualifying better biomarkers for NAFLD. Strongly associated with the epidemics of obesity and type 2 diabetes that are testing healthcare systems worldwide, NAFLD is an increasingly common cause of advanced liver disease that is characterized by substantial inter-patient variability in severity and rate of progression. Biomarkers under investigation in the project include genes that contribute to NAFLD progression. The NASH-DTA project has two parts: retrospective and prospective study. Retrospective study is based on analysing existing samples, prospective study will recruit 200 patients and collect new samples over 5 years.
The purpose of this tender process is to engage a supplier to provide metabolomic analysis on plasma samples from both a retrospective and prospective study using AbsolutelDQ Bile Acids kit and MxP Quant 500 Kit.
The Newcastle University Biosciences Institute is one of three research institutes established in 2019 following a restructure within the Faculty of Medical Sciences. Its members map across the biomedical research landscape. A number of major research projects are led from within the Institute including this investigation into genetic influences upon DNA methylation during development, ageing and disease of the human hip. This project funded by Versus Arthritis aims to investigate how a transcription factor (RUNX2) is regulated epigenetically in development and in later life, contributing to a range of traits and diseases including height, hip shape, facial morphology, osteoarthritis, and osteoporosis.
The purpose of this tender process is to engage a supplier to run Illumina MethylationEPIC and Infinium Global Screening Arrays to generate both DNA methylation and genotype data on 360 supplied DNA samples. Samples will be supplied for processing in 1 batch in early 2022 (Feb-March).
The Biomedical Engineering research hub in the School of Engineering, as well as other research groups in the Faculty of Science, Agriculture and Engineering and Faculty of Medical Sciences at Newcastle University, require AFM with PFM capabilities capabilities to support a wide range of research activities related to Medical Technologies.
Therefore, we are looking to purchase an AFM-PFM equipment that will enable us to nano-characterise new biomaterials and technologies for tissue engineering, analysis cell-cell and cell-materials interface in dry and wet/liquid state (e.g. property measurements of hydrogels, cells and tissues) and explore new healthcare research frontiers on the nanoscale. This purchase is being funded by the Wolfson Foundation.
The scope of this contract is for the supply, delivery and installation of the equipment detailed in the Invitation to Tender documents to the University, with after-sales support and 12 months warranty and maintenance.
Expressions of interest in this project can be made by registering via the University's etendering portal at: https://procontract.due-north.com/Advert/Index?advertId=1f5383a9-af95-ed11-811c-005056b64545
The contract reference is NU/1830
The deadline for expressing an interest in this tender is Tuesday 14th February 2023 at 16:00 hours GMT
The Biomedical Engineering research hub in the School of Engineering, as well as other research groups in the Faculty of Science, Agriculture and Engineering and Faculty of Medical Sciences at Newcastle University, require AFM with PFM capabilities capabilities to support a wide range of research activities related to Medical Technologies.
Therefore, we are looking to purchase an AFM-PFM equipment that will enable us to nano-characterise new biomaterials and technologies for tissue engineering, analysis cell-cell and cell-materials interface in dry and wet/liquid state (e.g. property measurements of hydrogels, cells and tissues) and explore new healthcare research frontiers on the nanoscale. This purchase is being funded by the Wolfson Foundation.
The scope of this contract is for the supply, delivery and installation of the equipment detailed in the Invitation to Tender documents to the University, with after-sales support and 12 months warranty and maintenance.
Expressions of interest in this project can be made by registering via the University's etendering portal at: https://procontract.due-north.com/Advert/Index?advertId=1f5383a9-af95-ed11-811c-005056b64545
The contract reference is NU/1830
The deadline for expressing an interest in this tender is Tuesday 14th February 2023 at 16:00 hours GMT
The University is requesting quotes for the purchase of a UV-vis-NIR double beam spectrometer. The spectrometer is required to provide steady-state absorption in support of the facility's time-resolved system which covers a range up to 2500 nm. To maximise usage as a National Facility and support training of doctoral candidates a complete turnkey solution is preferred, as well as a small footprint.
This purchase is being funded by the Engineering and Physical Sciences Research Council (EPSRC)
Please review the available documentation and provide a fully detailed quotation.
Express an interest and access the opportunity here:
https://procontract.due-north.com/Advert?advertId=3efab2ea-b0ab-ed11-811f-005056b64545
The University is requesting quotes for the purchase of a TCSPC photoluminescence spectrometer. To maximise usage as a National Facility and support training of doctoral candidates, a complete turnkey solution is preferred, as well as a small footprint.
This purchase is being funded by the Engineering and Physical Sciences Research Council (EPSRC).
Please review the available documentation and provide a fully detailed quotation.
Express an interest and access the opportunity here:
https://procontract.due-north.com/Advert?advertId=c5e86561-b3ab-ed11-811f-005056b64545