Caf1 is secreted from the bacterium Yersinia pestis to protect it from white blood cells during infection. It is formed from 15 kDa monomers that produce robust, flexible polymers up to 2 µm in length. We aim to create a spinout company that will initially produce Caf1 polymers and coated plasticware/microcarriers for the 2D cell culture market, predominantly focussed on laboratory research, expanding into commercial companies looking to scale up cell production. The Newcastle-based company will supply these products directly to customers, and through marketing partners who have established distribution networks. We are looking for a CEO/COO/Chairperson to work alongside Daniel Peters to develop a business plan that has considered the best market strategy for Caf1 in preparation for spinout formation and achieving the necessary fundraising
The initial brief of the executive will be to:
(1) Work with the existing team to lead in the creation of a viable 5 year business plan;
(2) Obtain university approval for the venture;
(3) a. Act for the company in the spin-out legal process and address all company formation matters;
b. Obtain founder academics’ and Newcastle University (including the Head of Company Creation) approval for appointment as CEO or agreed post supporting Daniel Peters
c. Provide to the appropriate university all matters necessary for Research England reporting requirements;
(4) Leading and work alongside the existing team to secure start up funding (venture capital and other) funding
Stage (5) will produce the funds by which the new start-up company can consider employing the executive going forward. It is expected, and the intent of the scheme, that the Executive will remain with the business following the end of the contract period. However, such appointment will be at the discretion of the board and appropriate university and will be subject to confirmation, typically at Stage 4 above
Clean Hydrogen is a company with technology offering a solution to reducing the cost of hydrogen to help meet climate change challenges. One of the main challenges associated with the UK's (and global) energy sector, in the medium term, is to decouple fossil fuels from the increasing demands for energy while ensuring supply chain security.
The initial brief of the executive will be to:
Phase (1) Produce a viable 5-year business plan and pitch deck;
Phase (2) Bring together the required collaboration team for producing a demonstrable minimum viable product;
Phase (3) Support preparation of company spin-out approval documents to present to University exec board
Phase (4) Complete the formation of the Spin-out
a. Act for the company in the spin-out legal process and address all company formation matters;]
b. Obtain founder academics and University approval for appointment as CEO.
Phase (5) Secure (venture capital and other) funding. Produce the funds by which the new start-up company can consider employing the executive going forward. It is expected, and the intent of the scheme, that the Executive will remain with the business following the end of the contract period. However, such appointment will be at the discretion of the board and university and will be subject to confirmation, typically at Stage 4 above]
One of NICRE’s key objectives is to connect with businesses in order to generate insight into the circumstances of rural enterprises. This business focussed objective is vital to providing an evidence base for policy and support services for rural enterprise, and also to informing NICRE’s business engagement and development plans. At the heart of this objective is NICRE’s business survey.
NICRE has a requirement to conduct a telephone survey of businesses operating in three specific regions in the UK (the West-Midlands, South-West and North-East). The survey will focus on aspects of business resilience and planning for both internal and external threats. Interviews will last around 20 minutes and should be conducted with a member of the senior management team of each organisation. Survey coverage should be broadly representative of the business population and sufficient to allow for (sub-regional) spatial, sectoral and firm size analysis. We require that the survey include non-farming and farm businesses and we propose to over-sample farm businesses and those located in rural areas. We therefore envisage a sampling structure which covers size, sector and rural/urban location within each of the three target regions
Neuroscience has revealed the importance of brainwaves for healthy and pathological brain function. Manipulating brainwaves can affect mood, memory, attention and sleep, with therapeutic benefits in conditions ranging from ADHD to anxiety to Alzheimer’s, but current neuromodulation techniques are limited.
Through research led by Newcastle University, we have demonstrated how ‘closed-loop’ neurostimulation (whereby brain signals control brain stimulation in a real-time feedback loop) can boost or suppress brainwave oscillations at different frequencies). Neudio combines closed-loop algorithms with non-invasive technologies (surface EEG recordings and musical stimulation) to regulate brainwaves. Effectively, our technology establishes a resonance between brain activity and music that enhances or suppresses brainwaves at specific frequencies.
The initial brief of the executive will be to:
Phase 1 – Write an ambitious business plan in line with ambitions and market opportunities
Phase 2 – Obtain IP Spin Out Committee Approval
Phase 3 – Complete spin-out legal process and act as company representative in legal formation of the company
Phase 4 – Prepare investment pitch deck and due diligence documents
Phase 5 – Initial negotiations to secure angel, seed or capital funding
Stage (5) will produce the funds by which the new start-up company can consider employing the executive going forward.
The pressure on the logistics sector is dramatically increasing over the years, from transport, to warehousing, distribution and end-user's optimization of day-to-day activities is becoming increasingly important. A key enabler for optimizing processes is IoT and ML technologies, a combination that could improve the entire supply chain which however is extremely challenging to achieve.
Madevo aims to develop a product proposition with diverse com communication capability. Madevo platform automates sensors onboarding process and directly provides clean data to businesses and end-users via phone or web applications. Without the limitation on the number of devices Madevo is proposing the first platform in the world to enable massive IoT deployments capable to connect with WiFi, 4G/5G and Low Orbit Satellites.
The initial brief of the executive will be to:
Phase 1 Opportunity Validation and Review and Amend Business Plan Creation:
Phase 2 Complete CRM Developed
Phase 3 Action CRM Plan
Phase 4 Securing Investment into the company
The Genomics Core Facility (GCF) within Newcastle University is a state-of-the-art Next-Generation Sequencing laboratory that specialises in single-cell and spatial transcriptomics applications and supports a wide range of sequencing-based research within the Faculty of Medical Sciences (FMS) and beyond. The sequencing technology currently available within the facility is based on a clonally amplified short-read approach. As part of an MRC equipment award the University are seeking to purchase a high-throughput, scalable, long-read single-molecule sequencer. The scope of the contract is for the supply of the equipment and proprietary consumables, delivery, installation, training, 4 years of maintenance and servicing cover to begin once the 12-month warranty period has expired and proprietary consumables for 5 years post installation (to be purchased as and when required). The sequencer will be operated by dedicated and experienced NGS staff and will play a central role in large-scale discovery and translational research programmes involving genomic, transcriptomic, epigenomic and single cell analysis.
To deliver on this vision, the platform must be able to provide full analytics on:
• Markets: The market landscape, market size and key players competing in this space.
o NICA track behaviours across-category, so we might want to highlight key market sectors to begin with.
• Trends: Existing and emerging innovations that fit with our areas of interest – keeping the data monitored over time as a permanent source of observation.
o NICA have developed a domain framework, which would need to be integrated.
• Behaviours: End-user insights to gauge appetite for and acceptability of existing solutions and identify opportunity gaps.
o NICA have developed coded behaviours as part of our ontology requiring semantic search – keeping the data monitored over time as a permanent source of observation.
The platform must also be configurable to include a suggested list of data sources (1,000 – 2,000 including but not limited to; stocks, companies, organisations and thought leaders) and have the capability to embed data visualisations from an external API / source, which will be fuelled by internal activity with our VOICE community.
Newcastle University requires three fluorescence and brightfield standard tissue culture incubator- based imaging systems for the automated imaging of cells in culture grown in standard tissue culture flasks, dishes and plates. The systems must be able to accommodate and schedule, multiple separate experiments each potentially requiring independent imaging parameters for example imaging frequency, magnification and fluorescence channel(s). The systems will be located and operated by the University’s BioImaging facility at three campus locations. Together they will form a live-cell imaging platform to serve the requirements of researchers at each location. The capabilities of each system or its associated software may need to be tailored depending on the research that it will support (see ITT). The main users of the system will be academic labs across the faculty of medical sciences.
The scope of the contract is for the delivery, installation and commissioning of three incubator-based multi-user imaging systems capable of both brightfield and fluorescence imaging modalities (as specified in Section 3). Pricing for warranty, maintenance and after sales service must be provided within Section 4 Pricing Schedule. Ex-demonstration or reconditioned systems will be considered. Please note that the University reserves the right not to make an award of contract.
We are seeking to appoint a supplier to produce a suite of 20-25 high quality short form videos. These videos will be used to promote various different degree subjects the target audiences in the UK and key international markets.
Alongside the main cuts, alternate edits for social channels and advertising campaigns will also be required. The supplier will work alongside internal teams to develop the video concepts, produce a production plan before completing the filming and editing work.
The videos must be produced in a style that meets the demands outlined in audience research conducted by the University in late 2022. For more information see the supplementary research presentation.
The supplier specifically is required to have the ability to provide the following services:
1) Produce up to 25 videos, one for each of our key degree subjects, each around 1-2 minutes long
2) Record up to 8 contributors and appropriate subject related b-roll of per video on location in Newcastle, with filming for the full project spread over 2 months
3) Source and license additional stock footage where required
4) Supply alternate cuts of the videos for use in different placements
5) Supply supplementary items for each video to facilitate distribution including:
6) Supply projects and raw assets for in-house use after completion
The scope of this contract is for the supply and installation of a nanoscale liquid handling system with all of the ancillary equipment required for the operation of the system. The offer must include training, for at least 3 personnel, for the safe operation of the equipment and 12 months warranty.
The problem that the Self -Enforcing Electronic Voting (SEEV) technology and proposed Spin Out company aims to address is a lack of "verifiability" in existing e-voting products in the commercial market. The proposal is to commercialize end-to-end (E2E) verifiable e-voting systems for real-world elections by the creation of a Spin Out company. E2E verifiability refers to the ability of voters to verify if their votes are cast-as-intended, recorded-as-cast, and for any interested party to publicly verify if all ballots are tallied-as-recorded, hence gaining confidence about the integrity of the whole election process.
At IngeniumAI we aim to address the unnecessary delays in disease diagnosis. Currently the diagnosis of many diseases takes far too long. For example, to receive a diagnosis the average pulmonary hypertension (PH) patient has 5.3 GP visits and 3 referrals, taking on average 2 years, 2 months. By this point treatment options are severely limited. If left untreated the average time to mortality is only 2 years, 6 months. Delays in diagnosis of PH are estimated to cost more than £27,000 per patient in additional healthcare resources and more than £100,000 in wider economic costs. The total UK cost is more than £250m per year, most of which could be eliminated with early screening. Globally these delays cause approximately 300,000 unnecessary deaths per year. We are responding to the opportunity by developing software to automatically analyse routine CT scans to enable early screening for diseases.
The Northumbria University team have developed two complementary ecotechnologies (namely, Solar2water and OptimumAirCon) though they may be targeting different market applications. Solar2water is an innovative atmospheric water generator (AWG) while OptimumAirCon is an innovative indirect evaporative cooling system (IEC).
The aim is to create a spin-out company ‘EcoTech Devices Limited’ which will market and sell products globally (esp. in hot climatic regions and/or off-grid requirement scenarios) based on the two ecotechnologies.
The initial brief of the executive will be to:
(1) Produce a viable 5 year business plan;
(2) Obtain university approval for the venture;
a. Act for the company in the spin-out legal process and address all company formation matters;
b. Provide to the appropriate university all matters necessary for Research England reporting requirements;
(3) Finalise market-ready product spec and validate TAM (Total Addressable Market)
(4) Engage with angels/VCs to attempt funding and promote to international partners
The project concerns work described in a Wellcome Trust Investigator Award which requires
the differentiation and functional assessment of macrophages from iPSC carrying mutations
of clonal haematopoiesis including TET2 frameshift, DNMT3A R882 and BRAF V600E.
Funding in the application is available for a research partner to supply these reagents.
The Newcastle University Translational and Clinical Research Institute is one of three
research institutes established in 2019 following a restructure within the Faculty of Medical
Sciences. Its members map across the biomedical research landscape. A number of major
research projects are led from within the Institute including the “NASH Disease Translational
Accelerator” (NASH-DTA) project. This project funded brings together clinicians and
scientists from prominent academic centres across Europe and industrial partners to
conduct research into advanced liver disease/cirrhosis caused by non-alcoholic fatty liver
disease (NAFLD). Their common goals are developing, validating and qualifying better
biomarkers for NAFLD. Strongly associated with the epidemics of obesity and type 2
diabetes that are testing healthcare systems worldwide, NAFLD is an increasingly common
cause of advanced liver disease that is characterized by substantial inter-patient variability in
severity and rate of progression. Biomarkers under investigation in the project include genes
that contribute to NAFLD progression.
The purpose of this tender process is to engage a supplier to provide clinical research
support, central laboratory services and to oversee biological sample transfers and provide
centralised laboratory processing of biological samples collected during the course of the
study.
The University is tendering for the provision of insurance policies, the requirement does not include broker services. The contract shall be divided into the following lots:
Lot 1 – Computer
Lot 2 – Combined Liability
Lot 3 – Management Liability
Lot 4 – Crime
Lot 5 – Terrorism
Lot 6 – Personal Accident & Travel
Lot 7 – Motor Fleet
supply and install workshop and laboratory equipment, broken-down into the following
Lots:
• Lot 1 – Lab Fume and Bio Cupboards and Water Purification Systems (supply, installation
and commissioning); 12 month service contract
• Lot 2 – Lab Fridges and Freezers;
• Lot 3 - Workshop CNC Equipment; 12 month service contract
• Lot 4 - Workshop Wire Eroder; 12 month service contract
• Lot 5 - Workshop Heavy Equipment.
• Lot 6 – Water Purification Systems
• Lot 7 - Fork Lift Truck
University of Newcastle upon Tyne t/a Newcastle UniversityNorth EastWAC-202024
Newcastle University Developments Ltd is a subsidiary of Newcastle University. Newcastle
University is a world leading research university working in partnership with Newcastle City
Council, NHS trusts and local stakeholders to regenerate the 29 acre site of the former city
General Hospital.
The University and Newcastle University Developments Ltd acquired 27 acres of the 29 acre site in April 2019 and since then have arrived at a clear Vision with accompanying objectives
as to what they want to achieve on the Campus for Ageing & Vitality (CAV). The University
intends to help people live longer and healthier lives by leveraging their international
reputation for ageing research and by providing a range of accommodation solutions on CAV.
The land to be regenerated by the Principal Development Partner is or will be under the
ownership of Newcastle University Developments Ltd.
Building on the success of the Helix site and National Innovation Centres for Aging and Data,
Newcastle University Developments Ltd (NUDL) are developing this site to be a world
leading example of intergenerational living co-locating education, health and a spectrum of
residential developments. Their vision is to help people live longer and healthier lives
through their global leadership in ageing and research, providing innovative solutions for
living, leisure, learning and employment from Newcastle, for the world.
Newcastle University, on behalf of the Newcastle Developments Ltd are looking to select
their principal development partner.