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Genomics England's Newborns Genome Programme is co-designing and running an NHS-embedded research study to explore the benefits, challenges, and practicalities of sequencing and analysing the genomes of newborns through using whole genome sequencing (WGS). The evidence gathered from the study will be evaluated rigorously to inform decisions about whether to roll-out this technology and develop the world's first national newborn screening programme that uses whole genome sequencing. One of the Programme's objectives is to understand how newborns' genomic and health data could be used for discovery research - for example, to enable the development of new diagnostics and treatments. With parents' consent, babies' genomes could be de-identified and added, alongside their health data, to Genomics England's National Genomic Research Library. This would enable carefully vetted academic, clinical, and life science industry researchers to develop novel diagnostics and treatments as well as understand how current therapies can be improved or repurposed, offering better outcomes to NHS patients. We are aware of particular sensitivities in society generally around the long-term storage and use of genomic and related health data in the context of research. To address these concerns, to date we have carried out small-scale in-house research with mothers or expectant mothers, where we have explored their feelings around how researchers could access and use newborns' genomes for research. However, this procurement aims to broaden these discussions, and unpack people's views on various options and approaches for the Programme's discovery research strategy. This procurement will support these aims, enabling in-depth exploration of attitudes and views on different types of data that could be drawn on for the Programme's research strategy, the acceptable and appropriate scope of research on these data, and specific mechanisms for creating a trustworthy system for doing so. To find out more about this opportunity and access the tender documents please register at https://genomicsengland.bravosolution.co.uk/genomicsengland/web/login.html and search for project_821
£100,000
Contract value
In this piece of work we are looking for a supplier to engage with ethnic minority community leaders to establish how Genomics England should work with members of those communities while designing and delivering our consent process. Additional information: In order to bid for this opportunity, you must register at our e-tendering portal (Bravo) using the link below. There, you will find all the relevant documentation by searching for "Consent Dialogue - Newborns" under project code "project_825". If you have any questions, you may contact us via email on supplier.engagement@genomicsengland.co.uk
£60,000
Contract value
To support the development of the Newborns Programme, we are seeking an agency to provide newborn photography that represents the parents we want to reach. We want to capture images of first-time parents feeling at ease that they've had the opportunity to find out early if their baby might need extra medical care as they grow up. If you are interested in bidding for this opportunity, please register at https://genomicsengland.bravosolution.co.uk/ and search for project_841
£60,000
Contract value
Genomics England are looking for a provider to support in digitising all the histopathology slides from the participants of the 100,000 Genomes Project so they can be transferred to the multi-modal research environment. The multi-modal project provides an enriched data set for cancer research by adding of imaging data from pathology slides and radiology images (e.g., x-ray, CT and MRI) alongside whole genome data. The multi-modal project aims are: - Complete the scanning and digitisation of the remaining 200,000 histopathology slides for the 100,000 Genomes Project participants. - Make accessible to researchers a secure library of linked genomic, clinical and imaging cancer data accompanied with the tooling needed to accelerate the understanding of the morphological, genomic and clinical changes that occur in cancer. - Lead the research community to generate new insights from the data to support diagnostic, prognostic and precision medicine discovery. How to apply The opportunity will go live on Monday 4th December. If you have not already done so, you will need to register on our Bravo portal https://public.bravosolution.co.uk/genomicsengland/web/login.html and inform us of the email address or supplier ID associated with your account. You will be invited to the opportunity and able to access the documents - all correspondence should be sent via the portal once the opportunity goes live.
£2,250,000
Contract value
Genomics England are looking for a provider to support in digitising all the histopathology slides from the participants of the 100,000 Genomes Project so they can be transferred to the multi-modal research environment. The multi-modal project provides an enriched data set for cancer research by adding of imaging data from pathology slides and radiology images (e.g., x-ray, CT and MRI) alongside whole genome data. The multi-modal project aims are: - Complete the scanning and digitisation of the remaining 200,000 histopathology slides for the 100,000 Genomes Project participants. - Make accessible to researchers a secure library of linked genomic, clinical and imaging cancer data accompanied with the tooling needed to accelerate the understanding of the morphological, genomic and clinical changes that occur in cancer. - Lead the research community to generate new insights from the data to support diagnostic, prognostic and precision medicine discovery. How to apply If you have not already done so, you will need to register on our Bravo portal https://public.bravosolution.co.uk/genomicsengland/web/login.html Please register on the e-tendering portal (Bravo) on the link provided. Once registered, you can find the opportunity under project title Services for slide digitisation - multi-modal or the project reference "project_867" All correspondence should be sent via the portal. To note, the project will go live and can be accessed from w/c 4th December 2023.
£2,250,000
Contract value
Genomics England are looking for a provider to support in digitising all the histopathology slides from the participants of the 100,000 Genomes Project so they can be transferred to the multi-modal research environment. The multi-modal project provides an enriched data set for cancer research by adding of imaging data from pathology slides and radiology images (e.g., x-ray, CT and MRI) alongside whole genome data. The multi-modal project aims are: - Complete the scanning and digitisation of the remaining 200,000 histopathology slides for the 100,000 Genomes Project participants. - Make accessible to researchers a secure library of linked genomic, clinical and imaging cancer data accompanied with the tooling needed to accelerate the understanding of the morphological, genomic and clinical changes that occur in cancer. - Lead the research community to generate new insights from the data to support diagnostic, prognostic and precision medicine discovery. How to apply If you have not already done so, you will need to register on our Bravo portal https://public.bravosolution.co.uk/genomicsengland/web/login.html Please register on the e-tendering portal (Bravo) on the link provided. Once registered, you can find the opportunity under project title Services for slide digitisation - multi-modal or the project reference "project_867" All correspondence should be sent via the portal.
£2,250,000
Contract value
Genomics England are looking for a provider to support in digitising all the histopathology slides from the participants of the 100,000 Genomes Project so they can be transferred to the multi-modal research environment. The multi-modal project provides an enriched data set for cancer research by adding of imaging data from pathology slides and radiology images (e.g., x-ray, CT and MRI) alongside whole genome data. The multi-modal project aims are: - Complete the scanning and digitisation of the remaining 200,000 histopathology slides for the 100,000 Genomes Project participants. - Make accessible to researchers a secure library of linked genomic, clinical and imaging cancer data accompanied with the tooling needed to accelerate the understanding of the morphological, genomic and clinical changes that occur in cancer. - Lead the research community to generate new insights from the data to support diagnostic, prognostic and precision medicine discovery. How to apply If you have not already done so, you will need to register on our Bravo portal https://public.bravosolution.co.uk/genomicsengland/web/login.html Please register on the e-tendering portal (Bravo) on the link provided. Once registered, you can find the opportunity under project title Services for slide digitisation - multi-modal or the project reference "project_867" All correspondence should be sent via the portal. To note, the project will go live and can be accessed from w/c 4th December 2023.
£2,250,000
Contract value