UK Public Sector Contracts & Tenders

VEAT NOTICE The University has a requirement to purchase an ion mobility mass spectrometer with associated liquid chromatography system for a dedicated proteomics facility. The University has published this VEAT notice and intends to award a contract to Bruker Ltd, following the expiry of 10 days from the date of publication of this notice. Additional information: The works, supplies or services can be provided only by a particular economic operator for the following reason: absence of competition for technical reasons as detailed below: • Achieve high sensitivity and near 100% ion utilisation through the use of trapped ion mobility or other technologies • Capable of separating chromatographically co-eluting positional isomers of peptides containing post-translational modifications by trapped ion mobility. • Provide high MS/MS scan speeds exceeding 120 Hz, to allow for high throughput sample analyses using short chromatographic gradients whilst maintaining high peptide identification rates • Perform real-time database searches of peptide spectra in order to deliver a complete peptide database search result by the end of the run. • Capable of measuring and incorporating Collisional Cross Section (CCS) values into the database search algorithm to improve peptide identification rates. • Capable of highly selective targeted assays such as Parallel Reaction Monitoring (PRM), ideally by selecting peptide targets through a combination of mass over charge and ion mobility • Mirror new proteomic analytical hardware provided to a partner laboratory and enable method and technology transfer between the labs.

VEAT NOTICE The University has a requirement to purchase an instrument that features the latest innovation for characterising biomolecular binding affinities. The University has published this VEAT notice and intends to award a contract to NanoTemper Technologies GmbH following the expiry of 10 days from the date of publication of this notice. Additional information: The works, supplies or services can be provided only by a particular economic operator for the following reason: absence of competition for technical reasons Explanation: Specific features of the system include the • Measurements are performed in solution (i.e. no immobilisation is required) • Capability to quantify interactions in complex solutions (crude extract, serum) • Means to determine binding constant over a wide range (5 nM - high millimolar) as well as stoichiometry and thermodynamic parameters • Power to work at low nanomolar concentrations • Advantage of small sample volumes (20 microliter) coupled with the capacity to run samples in high-throughput mode using standard 384 well-plate • Used detection modalities based on two techniques: Spectral shift detection and Temperature-Related Intensity Change (TRIC) • Microfluidics-free • Mass independent measurement i.e., the measurable molecular weight range is from 101-107 Da • Measure up to 384 datapoints per run • Advantage of small sample volumes (20 microliter) coupled with the capacity to run samples in high-throughput mode using standard SBS 384 well-plate format

VEAT NOTICE The University has a requirement to purchase a Lattice Light Sheet Microscope. The University has published this VEAT notice and intends to award a contract to Carl Zeiss following the expiry of 10 days from the date of publication of this notice. Additional information: Negotiated without a prior call for competition The works, supplies or services can be provided only by a particular economic operator for the following reason: absence of competition for technical reasons Explanation: • An inverted configuration which through the use of a meniscus lens and adaptive optics allows the use of widespread standard sample carriers such as dishes or multiwell slides and provides easier sample handling. In addition, adaptive optics in the detection light path can compensates for the distinct optical properties of the sample (especially important for plants). The inverted meniscus lens implementation also means that the lens never comes into contact with the sample media meaning that there is no dipping of lenses and no risk of cross contamination between samples. • Software wizards, automated alignment and monolithic design ensures that the system is very stable and does not require physical alignment by expert users meaning that the system can be setup and used by non-expert users easily and effectively, ideal for core facility use . • True simultaneous multicolour imaging using both cameras (Dual camera set up). A spatial light modulator with wavelength distinct areas is used for forming the lattice pattern allowing for multiple lasers to be used simultaneously while having an optimised pattern for each laser used. • The ZEISS Lattice Lightsheet 7 can be used with all standard sample carriers that come with a no. 1.5 coverslip for the bottom: o Slides o 35 mm dishes o Chamber slides o Multi-well plates • Integrated transmission LEDs and oblique detection which provide a DIC-like contrast, allowing easy sample location. Change from white to red transmission LEDs for more gentle illumination if necessary. • Specifically designed for this system, the unique 5-axis stage not only allows movement along the X, Y and Z axes, but also tilting with the highest precision in X and Y, compensating for even the smallest deviations in carrier dimensions or sample position

VEAT NOTICE The University has a requirement to purchase 6-off Broadband Ocean-Bottom Seismographs The University has published this VEAT notice and intends to award a contract to Nanaometrics following the expiry of 10 days from the date of publication of this notice.

The Institute for Computational Cosmology (ICC) at Durham University host part of the DiRAC national Tier-1 High Performance Computing (HPC) service. As part of this, a HPC Hardware Laboratory has been developed to investigate novel HPC technologies in all areas. We are currently funded to host a proof-of-concept liquid immersion cooled system, which will be made available to the UK research technical community to enable HPC systems administrators to grow in confidence with this technology, to visit the data centre, and learn how to manage immersion cooled servers. The total budget for this system is £250k including VAT (currently 20%) and must not be exceeded. The tender must be in UK pounds. It is a key requirement of this procurement project that the successful supplier will be prepared to build a strong and effective long-term collaborative partnership with the ICC. The University is keen to open opportunities to work closely with an industry partner to optimise this system and work towards future larger systems.

The University has a requirement to purchase 6-off Broadband Ocean-Bottom Seismographs The University has published this VEAT notice and intends to award a contract to Nanaometrics following the expiry of 10 days from the date of publication of this notice.

The University has a requirement to purchase a Lattice Light Sheet Microscope. The University has published this VEAT notice and intends to award a contract to Carl Zeiss following the expiry of 10 days from the date of publication of this notice.

Supply of Solar PV Panels

The University has a requirement to purchase an instrument that features the latest innovation for characterising biomolecular binding affinities. The University has published this VEAT notice and intends to award a contract to NanoTemper Technologies GmbH following the expiry of 10 days from the date of publication of this notice.

The University has a requirement to purchase an Orbitrap Gas Chromatograph Mass Spectrometer (GC-MS) with liquid, headspace and SPME arrow sample introduction systems. The instrument will be situated in the geography laboratories and will support researchers in multiple departments. The University has published this VEAT notice and intends to award a contract to Themo Fisher Scientific, following the expiry of 10 days from the date of publication of this notice.

The University has a requirement to purchase an ion mobility mass spectrometer with associated liquid chromatography system for a dedicated proteomics facility. The University has published this VEAT notice and intends to award a contract to Bruker Ltd, following the expiry of 10 days from the date of publication of this notice.